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aving a biphasic effect on IL-10. LA activates PKA signal transduction tion leads to stimulation of this inhibitory pathway, we examined the effects of LA on Lck phosphorylation. Western blot analysis revealed increased phospho-Lck levels right after remedy with LA for 10 minutes compared to untreated manage. No modifications had been detected in total Lck levels in the absence or presence of LA.

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